2002


1. Aemissegger A, Jaun B & Hilvert D
Investigation of the enzymatic and nonenzymatic Cope rearrangement of carbaprephenate to carbachorismate.
J. Org. Chem. 67 (2002) 6725-6730

2. Alexandrova E.S., Koralewski F., Titov M.I., Demin A.V., Kozyr A.V., Kolesnikov A.V., Tramontano A., Paul S., Thomas D., Gabibov A.G., Gnuchev N.V. & Friboulet A.
A structure-function study of a catalytic antiidiotypic antibody to the human erythrocyte acetylcholinesterase.
Bioorg. Khim. 28 (2002) 118-125

3. Andrievskaya OA, Buneva VN, Baranovskii AG, Gal'vita AV, Benzo ES, Naumov VA & Nevinsky GA
Catalytic diversity of polyclonal RNA-hydrolyzing IgG antibodies from the sera of patients with systemic lupus erythematosus.
Immunol. Letters 81 (2002) 191-198

4. Asada Y, Gouda H & Kollman PA
Molecular dynamics simulation study of the negative correlation in antibody AZ28-catalyzed oxy-cope rearrangement.
J. Am. Chem. Soc. 124 (2002) 12535-12542

5. Berisha HI, Bratut M, Bangale Y, Colasurdo G, Paul S & Said SI
New evidence for transmitter role of VIP in the airways: impaired relaxation by a catalytic antibody.
Pulm. Pharmacol. Ther. 15 (2002) 121-127

6. Betley JR, Cesaro-Tadic S, Mekhalfia A, Rickard JH, Denham H, Partridge LJ, Pluckthun A & Blackburn GM
Direct screening for phosphatase activity by turnover-based capture of protein catalysts.
Angew. Chem. 41 (2002) 775-777

7. Bolon DN, Voigt CA & Mayo SL
De novo design of biocatalysts.
Curr. Opin. Chem. Biol. 6 (2002) 125-129

8. Bosron WF & Hurley TD
Lessons from a bacterial cocaine esterase.
Nat. Struct. Biol. 9 (2002) 4-5

9. Briot A, Bujard M, Gouverneur V & Mioskowski C
Design and synthesis of haptens for the catalytic antibody-promoted dynamic kinetic resolution of oxazolin-5-ones.
Eur. J. Org. Chem. 2002 (2002) 139-144

10. Cross SSJ, Brady K, Stevenson JD, Sackin JR, Kenward N, Dietel A & Thomas NR
New variation on a theme: structure and mechanism of action of hydrolytic antibody 7F11, an aspartate rich relation of catalytic antibodies 17E8 and 29G11.
J. Immunol. Methods 269 (2002) 173-195

11. Damoiseaux R, Schultz PG & Johnsson K
Toward the generation of artificial O6-alkylguanine-DNA alkyltransferases: in vitro selection of antibodies with reactive cysteine residues.
Chembiochem 3 (2002) 573-575

12. Datta D, Vaidehi N, Xu X & Goddard WA
Mechanism for antibody catalysis of the oxidation of water by singlet dioxygen.
Proc. Natl. Acad. Sci. USA 99 (2002) 2636-2641

13. Delgado M, Spanka C, Kerwin LD, Wentworth P & Janda KD
A tunable hydrogel for encapsulation and controlled release of bioactive proteins.
Biomacromol. 3 (2002) 262-271

14. Deng SX, de Prada P & Landry DW
Anticocaine catalytic antibodies.
J. Immunol. Methods 269 (2002) 299-310

15. Dias S, Jovic F, Renard PY, Taran F, Créminon C, Mioskowski C & Grassi J
Immunologically driven chemical engineering of antibodies for catalytic activity.
J. Immunol. Methods 269 (2002) 81-98

16. D'Souza LJ, Gigant B, Knossow M & Green BS
Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
J. Am. Chem. Soc. 124 (2002) 2114-2115

17. Florez-Alvarez J, Brocklehurst K, Gallacher G & Resmini M
Synthesis of an aminoalcohol hapten for the generation of catalytic antibodies.
Tetrahedron Lett. 43 (2002) 171-174

18. Franqueville E, Stamatis H, Loutrari H, Friboulet A & Kolisis F
Studies on the catalytic behavior of a cholinesterase-like abzyme in an AOT microemulsion system.
J. Biotechnol. 97 (2002) 177-182

19. Gabibov AG, Friboulet A, Thomas D, Demin AV, Ponomarenko NA, Vorobiev II, Pillet D, Paon M, Alexandrova EA, Telegin GB, Reshetnyak AV, Grigorieva OV, Gnuchev NV, Malishkin KA & Genkin DD
Antibody proteases: induction of catalytic response.
Biochemistry (Moscow) 67 (2002) 1168-1179

20. Gauchet C, Taran F, Renard PY, Créminon C, Grassi J, Pradelles P & Mioskowski C
The use of enzyme immunoassays for the detection of abzymatic activities. Application to an enantioselective thioacetal hydrolysis activity.
J. Immunol. Methods 269 (2002) 133-145

21. Gildersleeve J, Janes J, Ulrich H, Yang P, ,Barbas C & Schultz PG
Development of a genetic selection for catalytic antibodies.
Bioorg. Med. Chem. Lett. 12 (2002) 1691-1694

22. Glushkov A
Immunostimulation of the chemical-induced carcinogenesis in the phase of initiation MH-G 0166.
Med. Hypoth. 59 (2002) 501-503

23. Golinelli-Pimpaneau B
Structural diversity of antibody catalysts.
J. Immunol. Methods 269 (2002) 157-171

24. Gonçalves O, Dintinger T, Blanchard D & Tellier C
Functional mimicry between anti-Tendamistat antibodies and alpha-amylase.
J. Immunol. Methods 269 (2002) 29-37

25. Gozin Y & Hilvert D
Steric and electronic effects on an antibody-catalyzed Diels-Alder reaction.
Helv. Chim. Acta 85 (2002) 4328-4336

26. Gramatikova S, Mouratou B, Stetefeld J, Mehta PK & Christen P
Pyridoxal-5'-phosphate-dependent catalytic antibodies.
J. Immunol. Methods 269 (2002) 99-110

27. Hifumi E, Mitsuda Y, Ohara K & Uda T
Targeted destruction of the HIV-1 coat protein gp41 by a catalytic antibody light chain.
J. Immunol. Methods 269 (2002) 283-298

28. Hotta K, Wilson IA & Hilvert D
Probing ligand recognition in the decarboxylase antibody 21D8: implications for the catalytic mechanism.
Biochemistry 41 (2002) 772-779

29. Hugot M, Bensel N, Vogel M, Reymond MT, Stadler B, Reymond JL & Baumann U
A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue.
Proc. Natl. Acad. Sci. USA 99 (2002) 9674-9678

30. Isomura S, Ashley JA, Wirsching P & Janda KD
Antibody-catalyzed cleavage of D-Ala-D-Lac dipepsipeptide: an immunological approach to the problem of vancomycin resistance.
Bioorg. Med. Chem. Letters 12 (2002) 861-864

31. Isomura S, Hoffman TZ, Wirsching P & Janda KD
Synthesis, properties, and reactivity of cocaine benzoylthio ester possessing the cocaine absolute configuration.
J. Am. Chem. Soc. 124 (2002) 3661-3668

32. Jiang X, Ookubo Y, Fujii I, Nakano H & Yamane T
Expression of Fab fragment of catalytic antibody 6D9 in an Escherichia coli in vitro coupled transqcription/translation system.
FEBS Letters 514 (2002) 290-294

33. Johnson G & Moore SW
Catalytic antibodies with acetylcholinesterase activity.
J. Immunol. Methods 269 (2002) 13-28

34. Johnson G. & Moore S.W.
Idiotypic mimicry of a catalytic antibody active site.
Mol. Immunol. 39 (2002) 273-288

35. Jones LH, Altobell LJ, MacDonald MT, Boyle NA, Wentworth P, Lerner RA & Janda KD
Active immunization with a glycolipid transition state analogue protects against endotoxic shock.
Angew. Chem. 41 (2002) 4241-4244

36. Kakinuma H, Fujii I & Nishi Y
Selective chemotherapeutic strategies using catalytic antibodies: a common pro-moiety for antibody-directed abzyme prodrug therapy.
J. Immunol. Methods 269 (2002) 269-281

37. Khomutov RM
Design of pyridoxal 5'-phosphate dependent catalytic antibodies.
Biochemistry (Moscow) 67 (2002) 1085-1088

38. Kim GT, Wenz M, Park JI, Hasserodt J & Janda KD
Polyene substrates with unusual methylation patterns to probe the active sites of three catalytic antibodies.
Bioorg. Med. Chem. 10 (2002) 1249-1262

39. Kim SP, Leach AG & Houk KN
The origins of non-covalent catalysis of intermolecular Diels-Alder reactions by cyclodextrins, self-assembling capsules, antibodies and RNAses.
J. Org. Chem. 67 (2002) 4250-4260

40. Kit Y, Kuligina E, Semenov D & Richter V
Oligodeoxyadenylate stimulates the protein kinase activity of anti-DNA sIgA from human milk.
Acta Biochim. Pol. 49 (2002) 291-294

41. Kozyr AV, Sashchenko LP, Kolesnikov AV, Zelenova NA, Khaidukov SV, Ignatova AN, Bobik TV, Gabibov AG, Alekberova ZS, Suchkov SV & Gnuchev NV
Anti-DNA autoantibodies reveal toxicity to tumor cell lines.
Immunol. Letters 80 (2002) 41-47

42. Lacroix-Desmazes S, Bayry J, Misra N, Horn MP, Villard S, Pashov A, Stieltjes N, d'Oiron R, Saint-Remy JM, Hoebeke J, Kazatchkine MD, Reinbolt J, Mohanty D & Kaveri SV
The prevalence of proteolytic antibodies against factor VIII in hemophilia A.
N. Engl. J. Med. 346 (2002) 662-667

43. Lacroix-Desmazes S, Misra N, Bayry J, Villard S, Kazatchkine MD & Kaveri SV
Antibodies with hydrolytic activity towards factor VIII in patients with hemophilia A.
J. Immunol. Methods 269 (2002) 251-256

44. Lindner AB, Kim SH, Schindler DG, Eshhar Z & Tawfik DS
Esterolytic antibodies as mechanistic and structural models of hydrolases. A quantitative analysis.
J. Mol. Biol. 320 (2002) 559-572

45. Luo YM, Mu Y, Wei JY, Yan GL & Luo GM
Studies on the optimal expression condition, purification and its characterization of ScFv-2F3.
Sheng Wu Gong Cheng Xue Bao 18 (2002) 74-78

46. Maggiotti V, Resmini M & Gouverneur V
Unprecedented regiocontrol using an aldolase I antibody.
Angew. Chem. 41 (2002) 1012-1014

47. Mouratou B & Guesdon JL
A method for the detection and screening of catalytic anti-DNA antibodies.
J. Immunol. Methods 269 (2002) 147-155

48. Mouratou B, Rouyre S, Pauillac S & Guesdon JL
Development of nonradioactive microtiter plate assays for nuclease activity.
Anal. Biochem. 309 (2002) 40-47

49. Nathan C
Catalytic antibody bridges innate and adaptative immunity.
Science 298 (2002) 2143-2144

50. Nevinsky GA & Buneva VN
Human catalytic RNA- and DNA-hydrolyzing antibodies.
J. Immunol. Methods 269 (2002) 235-249

51. Nicholas KM, Wentworth P, Harwig CW, Wentworth AD, Shafton A & Janda KD
A cofactor approach to copper-dependent catalytic antibodies.
Proc. Natl. Acad. Sci. USA 99 (2002) 2648-2653

52. Nishi Y
Evolution of catalytic antibody repertoire in autoimmune mice.
J. Immunol. Methods 269 (2002) 213-233

53. Nishiyama Y, TaguCHI H, Luo JQ, Zhou YX, Burr G, Karle S & Paul S
Covalent reactivity of phosphonate monophenyl esters with serine proteinases: an overlooked feature of presumed transition state analogs.
Arch. Biochem. Biophys. 402 (2002) 281-288

54. Ostler EL, Dean CJ, Barber N, Valeri M, James S, Resmini M, Boucher G, Romanov N, Brocklehurst K & Gallacher G
A rat monoclonal antibody that catalyses the hydrolysis of a nitrophenyl--lactam.
Biochem. Biophys. Res. Commun. 299 (2002) 273-276

55. Ostler EL, Resmini M, Boucher G, Romanov N, Brocklehurst K & Gallacher G
Polyclonal antibody-catalysed hydrolysis of a beta-lactam.
Chem. Commun. 9 (2002) 226-227

56. Ostler EL, Resmini M, Brocklehurst K & Gallacher G
Polyclonal catalytic antibodies.
J. Immunol. Methods 269 (2002) 111-124

57. Piatesi A & Hilvert D
Optimized production of the Diels-Alderase antibody 1E9 as a chimeric Fab.
Can. J. Chem. 80 (2002) 657-664

58. Pillet D, Paon M, Vorobiev II, Gabibov AG, Thomas D & Friboulet A
Idiotypic network mimicry and antibody catalysis: lessons for the elicitation of efficient anti-idiotypic protease antibodies.
J. Immunol. Methods 269 (2002) 5-12

59. Ponomarenko NA, Durova OM, Vorobiev II, Aleksandrova ES, Telegin GB, Chamborant OG, Sidorik LL, Suchkov SV, Alekberova ZS, Gnuchev NV & Gabibov AG
Catalytic antibodies in clinical and experimental pathology: human and mouse models.
J. Immunol. Methods 269 (2002) 197-211

60. Pungente MD, Weiler L & Ziltener HJ
Antibody-catalyzed formation of a 14-membered ring lactone.
Can. J. Chem. 80 (2002) 1643-1645

61. Reymond JL
Detection strategies for catalytic antibodies.
J. Immunol. Methods 269 (2002) 125-131

62. Ricoux R, Girgenti E, Sauriat-Dorizon H, Blanchard D et Mahy JP
Regioselective nitration of phenol induced by catalytic antibodies.
J. Protein Chem. 21 (2002) 473-477

63. Ricoux R, Sauriat-Dorizon H, Girgenti E, Blanchard D & Mahy JP
Hemoabzymes: towards new biocatalysts for selective oxidations.
J. Immunol. Methods 269 (2002) 39-57

64. Satchi-Fainaro R, Wrasidlo W, Lode HN & Shabat D
Synthesis and characterization of a catalytic antibody-HPMA copolymer-conjugate as a tool for tumor selective prodrug activation.
Bioorg. Med. Chem. 10 (2002) 3023-3029

65. Schowen RL
The elicitation of carboxylesterase activity in antibodies by reactive immunization with labile organophosphorus antigens: a role for flexibility.
J. Immunol. Methods 269 (2002) 59-65

66. Schultz PG & Lerner RA
Completing the circle.
Nature 418 (2002) 485

67. Schultz PG, Yin J & Lerner RA
The chemistry of the antibody molecule.
Angew. Chem. 41 (2002) 4427-4437

68. Shi ZD, Yang BH, Zhao JJ, Wu YL, Ji YY & Yeh M
Enatioselective hydrolysis of naproxen ethyl ester catalyzed by monoclonal antibodies.
Bioorg. Med. Chem. 10 (2002) 2171-2175

69. Shulman A, Sitry D, Shulman H & Keinan E
Highly efficient antibody-catalyzed deuteration of carbonyl compounds.
Chem. Eur. J. 8 (2002) 229-239

70. Stepaniak L
Isolation and partial characterization of catalytic antibodies with oligonuclease activity from bovine colostrum.
Prep. Biochem. Biotechnol. 32 (2002) 17-28

71. Tagushi H, Burr G, Karle S, Planque S, Zhou YX, Paul S & Nishiyama Y
A mechanism-based probe for gp120-hydrolyzing antibodies.
Bioorg. Med. Chem. Lett. 12 (2002) 3167-3170

72. Tanaka F
Catalytic antibodies as designer proteases and esterases.
Chem. Rev. 102 (2002) 4885-4906

73. Tanaka F & Barbas III CF
Reactive immunization: a unique approach to catalytic antibodies.
J. Immunol. Methods 269 (2002) 67-79

74. Tantillo DJ & Houk KN
Transition state docking: a probe for noncovalent catalysis in biological systems. Application to antibody-catalyzed ester hydrolysis.
J. Comput. Chem. 23 (2002) 84-95

75. Tao H & Cornish VW
Milestones in directed enzyme evolution.
Curr. Opin. Chem. Biol. 6 (2002) 858-864

76. Tellier C
Exploiting antibodies as catalysts: potential therapeutic applications.
Transfus. Clin. Biol. 9 (2002) 1-8

77. Van Den Berg RJBHN, Noort D, Van Der Marel GA, Van Boom JH & Benschop HP
Synthesis of pseudo-disaccharide analogues of lipid A: haptens for the generation of antibodies with glycosidase activity towards lipid A.
J. Carbohydr. Chem. 21 (2002) 167-188

78. Wang J, Han Y, Liang S & Wilkinson MF
Catalytic antibody therapy against the insecticide carbaryl.
Biochem. Biophys. Res. Commun. 291 (2002) 605-610

79. Wentworth P
Tech. Sight. Antibody design by man and nature.
Science 296 (2002) 2247-2249

80. Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschnmoser A & Lerner RA
Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation.
Science 298 (2002) 2195-2199

81. Xu X, Muller RP & Goddard WA
The gas phase reaction of singlet dioxygen with water: a water-catalyzed mechanism.
Proc. Natl. Acad. Sci. USA 99 (2002) 3376-3381

82. Zhou YX, Karle S, Tagushi H, Planque S, Nishiyama Y & Paul S
Prospects for immunotherapeutic proteolytic antibodies.
J. Immunol. Methods 269 (2002) 257-268




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