1994


1. Boger DL, Lerner RA & Cravatt BF
Synthesis of a functionalized rigid bicyclol[2.2.1]heptane: A useful hapten for eliciting catalytic antibodies.
J. Org. Chem. 59 (1994) 5078-5079

2. Braisted AC & Schultz PG
An antibody-catalyzed oxy-Cope rearrangement.
J. Am. Chem. Soc. 116 (1994) 2211-2212

3. Buneva VN, Andrievskaya OA, Romannikova IV, Gololobov GV, Yadav RP, Yamkovoi VI & Nevinsky GA
Interaction of catalytically active antibodies with oligonucleotides.
Molec. Biol. 28 (1994) 483-486

4. Campbell DA, Gong B, Kochersperger LM, Yonkovich S, Gallop MA & Schultz PG
Antibody-catalyzed prodrug activation.
J. Am. Chem. Soc. 116 (1994) 2165-2166

5. Chen Y, Reymond JL & Lerner RA
An antibody-catalyzed 1,2-rearrangement of carbon-carbon bonds.
Angew. Chem. 33 (1994) 1607-1609

6. Cravatt BF, Ashley JA, Janda KD, Boger DL & Lerner RA
Crossing extreme mechanistic barriers by antibody catalysis: Syn elimination to a cis olefin.
J. Am. Chem. Soc. 116 (1994) 6013-6014

7. Crespeau H, Laouar A & Rochu D
Un abzyme DNase polyclonal produit par la méthode de l'image interne anti-idiotypique.
C. R. Acad. Sci. Paris 317 (1994) 819-823

8. Friboulet A, Izadyar L, Avalle B, Roseto A & Thomas D
Abzyme generation using an anti-idiotypic antibody as the "internal image" of an enzyme active site.
Appl. Biochem. Biotechnol. 47 (1994) 229-237

9. Gabibov AG, Gololobov GV, Makarevich OI, Schourov DV, Chernova EA & Yadav RP
DNA-hydrolysing autoantibodies.
Appl. Biochem. Biotechnol. 47 (1994) 293-302

10. Gao QS, Sun M, Tyutyulkova S, Webster D, Rees A, Tramontano A, Massey RJ & Paul S
Molecular cloning of a proteolytic antibody light chain.
J. Biol. Chem. 269 (1994) 32389-32393

11. Golinelli-Pimpaneau B, Gigant B, Bizebard T, Navaza J, Saludjian P, Zemel R, Tawfik DS, Eshhar Z, Green BS & Knossow M
Crystal structure of a catalytic antibody Fab with esterase-like activity.
Structure 2 (1994) 175-183

12. Gololobov GV, Mikhalap SV, Starov AV, Kolesnikov AF & Gabibov AG
DNA-protein complexes: natural targets for DNA-hydrolyzing antibodies.
Appl. Biochem. Biotechnol. 47 (1994) 305-314

13. Guo J, Huang W & Scanlan TS
Kinetic and mechanistic characterization of an efficient hydrolytic antibody: Evidence for the formation of an acyl intermediate.
J. Am. Chem. Soc. 116 (1994) 6062-6069

14. Haynes MR, Stura EA, Hilvert D & Wilson IA
Crystallization and preliminary structural studies of a chorismate mutase catalytic antibody complexed with a transition state analog.
Proteins 18 (1994) 198-200

15. Haynes MR, Stura EA, Hilvert D & Wilson IA
Routes to catalysis: Structure of a catalytic antibody and comparison with its natural counterpart.
Science 263 (1994) 646-652

16. Hilvert D
Catalytic antibodies.
Current Opinions Struct. Biol. 4 (1994) 612-617

17. Hirschmann R, Smith AB, Taylor CM, Benkovic PA, Taylor SD, Yager KM, Sprengeler PA & Benkovic SJ
Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids.
Science 265 (1994) 234-237

18. Hsieh LC, Stephans JC & Schultz PG
An efficient antibody-catalyzed oxygenation reaction.
J. Am. Chem. Soc. 116 (1994) 2167-2168

19. Iwabuchi Y, Miyashita H, Tanimura R, Kinoshita K, Kikuchi M & Fujii I
Regioselective and stereoselective deprotonation of acylated carbohydrates via catalytic antibodies.
J. Am. Chem. Soc. 116 (1994) 771-772

20. Jacobsen EN & Finney NS
Synthetic and biological catalysts in chemical synthesis: how to assess practical utillity.
Chem. Biol. 1 (1994) 85-90

21. Jacobsen JR & Schultz PG
Antibody catalysis of peptide bond formation.
Proc. Natl. Acad. Sci. USA 91 (1994) 5888-5892

22. Jahangiri GK & Reymond JL
Antibody-catalyzed hydrolysis of enol ethers. 2. Structure of the antibody-transition state complex and origin of the enantioselectivity.
J. Am. Chem. Soc. 116 (1994) 11264-11274

23. Janda KD, Lo CHL, Li T, Barbas III CF, Wirsching P & Lerner RA
Direct selection for a catalytic mechanism from combinatorial antibody libraries.
Proc. Natl. Acad. Sci. USA 91 (1994) 2532-2536

24. Jespersen TM, Bols M, Sierks MR & Skrydstrup T
Synthesis of isofagomine, a novel glycosidase inhibitor.
Tetrahedron 50 (1994) 13449-13460

25. Khettal B, Delauzon S, Desfosses B, Ushida S & Marquet A
A catalytic antibody isomerizing a delta(5)-3-ketosteroid.
C. R. Acad. Sci. Paris 317 (1994) 381-385

26. Kitazume T, Tsukamoto T & Yoshimura K
A catalytic antibody elicited by a hapten of tetrahedral carbon-type.
J. Chem. Soc., Chem. Commun. 11 (1994) 1355-1356

27. Koch A, Reymond JL & Lerner RA
Antibody-catalyzed activation of unfunctionalized olefins for highly enantioselective asymmetric epoxidation.
J. Am. Chem. Soc. 116 (1994) 803-804

28. Li T, Janda KD, Ashley JA & Lerner RA
Antibody catalyzed cationic cyclization.
Science 264 (1994) 1289-1293

29. Luo G, Zhu Z, Ding L, Gao G, Sun Q, Liu Z, Yang T & Shen J
Generation of selenium-containing abzyme by using chemical mutation.
Biochem. Biophys. Res. Commun. 198 (1994) 1240-1247

30. Malachowski WP & Coward JK
The chemistry of phosphapeptides: Formation of functionalized phosphonachloridates under mild conditions and their reaction with alcohols and amines.
J. Org. Chem. 59 (1994) 7616-7624

31. Malachowski WP & Coward JK
The chemistry of phosphapeptides: Investigations on the synthesis of phosphonamidate, phosphonate, and phosphinate analogues of glutamyl-g-glutamate.
J. Org. Chem. 59 (1994) 7625-7634

32. Martin MT, Angeles TS, Sugasawara R, Aman NI, Napper AD, Darsley MJ, Sanchez RI, Booth P & Titmas RC
Antibody-catalyzed hydrolysis of an unsubstituted amide.
J. Am. Chem. Soc. 116 (1994) 6508-6512

33. Martin SF, Wagman AS, Zipp GG & Gratchev MK
General route to phosphonodithioic acid derivatives.
J. Org. Chem. 59 (1994) 7957-7958

34. Matsuura K, Yamamoto K & Sinohara H
Amidase activity of human Bence Jones proteins.
Biochem. Biophys. Res. Commun. 204 (1994) 57-62

35. McCafferty J, Fitzgerald KJ, Earnshaw, Chiswell DJ, Link J, Smith R & Kenten J
Selection and rapid purification of murine antibody fragments that bind a transition-state analog by phage display.
Appl. Biochem. Biotechnol. 47 (1994) 157-173

36. Miyashita H, Hara T, Tanimura R, Tanaka F, Kikuchi M & Fujii I
A common ancestry for multiple catalytic antibodies generated against a single transition-state analog.
Proc. Natl. Acad. Sci. USA 91 (1994) 6045-6049

37. Mody R, Tramontano A & Paul S
Spontaneous hydrolysis of vasoactivr intestinal peptide in neutral aqueous solution.
Int. J. Pept. Prot. Res. 44 (1994) 441-447

38. Nakatani T, Umeshita R, Hiratake J, Shinzaki A, Suzuki T, Nakajima H & Oda J
Characterization of a catalytic antibody for stereoselective ester hydrolysis - a catalytic residue and mode of product inhibition.
Bioorg. Med. Chem. 2 (1994) 457-468

39. Paul S
Catalytic activity of anti-ground state antibodies, antibody subunits, and human autoantibodies.
Appl. Biochem. Biotechnol. 47 (1994) 241-253

40. Posner B, Smiley J, Lee I & Benkovic S
Catalytic antibodies: perusing combinatorial libraries.
Trends Biochem. Sci. 19 (1994) 145-150

41. Reymond JL, Reber JL & Lerner RA
Enantioselective, multigram-scale synthesis with a catalytic antibody.
Angew. Chem. 33 (1994) 475-477

42. Roberts VA, Stewart J, Benkovic SJ & Getzoff ED
Catalytic antibody model and mutagenesis implicate arginine in transition-state stabilization.
J. Mol. Biol. 235 (1994) 1098-1116

43. Savitsky AP, Demcheva MV, Mantrova EY & Ponomarev GV
Monoclonal antibodies against metalloporphyrins. Specificity of interaction with structural different metallophophyrins.
FEBS Letters 355 (1994) 314-316

44. Savitsky AP, Nelen MI, Yatsmirsky AK, Demcheva MV, Ponomarev GV & Sinikov IV
Kinetics of oxidation of o-dianisidine by hydrogen peroxide in the presence of antibody complexes of iron(III) coproporphyrin.
Appl. Biochem. Biotechnol. 47 (1994) 317-327

45. Shevlin CG, Hilton S & Janda KD
Automation of antibody catalysis. A practical methodology for the use of catalytic antibodies in organic synthesis.
Bioorg. Med. Chem. Letters 4 (1994) 297-302

46. Shokat K, Uno T & Schultz PG
Mechanistic studies of an antibody-catalyzed elimination reaction.
J. Am. Chem. Soc. 116 (1994) 2261-2270

47. Siuzdak G, Krebs JF, Benkovic SJ & Dyson HJ
Binding of hapten to a single-chain catalytic antibody demonstrated by electrospray mass spectrometry.
J. Am. Chem. Soc. 116 (1994) 7937-7938

48. Smiley JA & Benkovic SJ
Selection of catalytic antibodies for a biosynthetic reaction from a combinatorial cDNA library by complementation of an auxotrophic Escherichia coli: antibodies for orotate decarboxylation.
Proc. Natl. Acad. Sci. USA 91 (1994) 8319-8323

49. Smith AB, Taylor CM, Benkovic & Hirschmann R
Peptide bond formation via catalytic antibodies: Synthesis of a novel phosphonate diester hapten.
Tetrahedron Letters 35 (1994) 6853-6856

50. Smith RM, Yuan P, Weiner DP, Dutton CR & Hansen DE
An approach to sequence-specific antibody proteases. The use of haptens mimicking both a transition state and a distorted ground state.
Appl. Biochem. Biotechnol. 47 (1994) 329-342

51. Stephens DB, Wilmore BH & Iverson BL
Polyclonal antibodies and catalysis.
Bioorg. Med. Chem. 2 (1994) 653-658

52. Stewart JD, Krebs JF, Siuzdak G, Berdis AJ, Smithrud DB & Benkovic SJ
Dissection of an antibody-catalyzed reaction.
Proc. Natl. Acad. Sci. USA 91 (1994) 7404-7409

53. Stewart JD, Roberts VA, Thomas NR, Getzoff ED & Benkovic SJ
Site-directed mutagenesis of a catalytic antibody: An arginine and a histidine residue play key roles.
Biochemistry 33 (1994) 1994-2003

54. Suga H, Ersoy O, Tsumuraya T, Lee J, Sinskey AJ & Masamume S
Esterolytic antibodies induced to haptens with a 1,2-amino alcohol functionality.
J. Am. Chem. Soc. 116 (1994) 487-494

55. Suga H, Ersoy O, Williams SF, Tsumuraya T, Margolies MN, Sinskey AJ & Masamune S
Catalytic antibodies generated via heterologous immunization.
J. Am. Chem. Soc. 116 (1994) 6025-6026

56. Suga H, Tanimoto N, Sinskey AJ & Masamune S
Glycosidase antibodies induced to a half-chair transition-state analog.
J. Am. Chem. Soc. 116 (1994) 11197-11198

57. Sun M, Gao QS, Li L & Paul S
Proteolytic activity of an antibody light chain.
J. Immunol. 153 (1994) 121-126

58. Suzuki H
Recent advances in abzyme studies.
J. Biochem. 115 (1994) 623-628

59. Suzuki H, Sasaki K, Mukouyama EB, Kawamura-Konishi Y, Wada Y & Ono M
Delayed appearance of the catalytic activity by immunization of a rabbit compared with the hapten binding.
Biochem. Mol. Biol. Int. 34 (1994) 27-35

60. Tarasow TM, Lewis C & Hilvert D
Investigation of medium effects in a family of decarboxylase antibodies.
J. Am. Chem. Soc. 116 (1994) 7959-7963

61. Tawfik D, Eshhar Z & Green BS
Catalytic antibodies: a critical assessment.
Mol. Biotechnol. 1 (1994) 87-103

62. Teraishi K, Saito M, Fujii I & Nakamura H
Design of the hapten for the induction of antibodies catalyzing aldol reaction.
J. Molec. Graph. 12 (1994) 282-285

63. Thomas NR
Hapten design for the generation of catalytic antibodies.
Appl. Biochem. Biotechnol. 47 (1994) 345-372

64. Titmas RC, Angeles TS, Sugasawara R, Aman N, Darsley MJ, Blackburn GM & Martin MT
Aspects of antibody-catalyzed primary amide hydrolysis.
Appl. Biochem. Biotechnol. 47 (1994) 277-290

65. Tramontano A
Immune recognition, antigen design, and catalytic activity production.
Appl. Biochem. Biotechnol. 47 (1994) 257-2273

66. Uno T, Gong B & Schultz PG
Stereoselective antibody-catalyzed oxime formation.
J. Am. Chem. Soc. 116 (1994) 1145-1146

67. Vanvranken DL, Panomitros D & Schultz PG
Catalysis of carbamate hydrolysis by an antibody.
Tetrahedron Letters 35 (1994) 3873-3876

68. Wilmore BH & Iverson BL
Phosphate versus phosphorothioate haptens for the production of catalytic polyclonal antibodies.
J. Am. Chem. Soc. 116 (1994) 2181-2182

69. Wilson IA & Stanfield RL
Antibody-antigen interactions: New structures and new conformational changes.
Current Opinions Struct. Biol. 4 (1994) 857-867

70. Yu JH, Hsieh LS, Kochersperger L, Yonkovich S, Stephans JC, Gallop MA & Schultz PG
Progress towards an antibody glycosidase.
Angew. Chem. 33 (1994) 339-341

71. Zemel R, Schindler DG, Tawfik DS, Eshhar Z & Green BS
Differences in the biochemical properties of esterolytic antibodies correlate with structural diversity.
Mol. Immunol. 31 (1994) 127-137

72. Zhou GW, Guo J, Huang W, Fletterick RJ & Scanlan TS
Crystal structure of a catalytic antibody with a serine protease active site.
Science 265 (1994) 1059-1064

73. Zhu Z, Ding L, Luo GM, Liu Z, Sun Q, Yang T & Shen J
Some physicochemical and enzymic properties of selenium-containing abzyme.
Biochem. Biophys. Res. Commun. 202 (1994) 1645-1650




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