1997


1. Akashi S, Kato K, Torizawa T, Dohmae N, Yamaguchi H, Kamachi M, Harada A, Imanaka T, Shimada I & Takio K
Structural characterization of mouse monoclonal antibody 13-1 against a porphyrin derivative: identification of a disulfide bond in CDR-H3 of Mab 13-1.
Biochem. Biophys. Res. Commun. 240 (1997) 566-572

2. Baca M, Scanlan TS, Stephenson RC & Wells JA
Phage display of a catalytic antibody to optimize affinity for transition-state analog binding.
Proc. Natl. Acad. Sci. USA 94 (1997) 10063-10068

3. Barbas III CF, Heine A, Zhong G, Hoffmann T, Gramatikova S, Björnestedt R, List B, Anderson J, Stura EA, Wilson IA & Lerner RA
Immune versus natural selection: antibody aldolase with enzymatic rates but broader scope.
Science 278 (1997) 2085-2092

4. Carter S, Resmini M, Simms C, Sreedharan SK, Gallacher G & Brocklehurst K
Are polyclonal catalytic antibodies heterogeneous?
Biochem. Soc. Trans. 25 (1997) 86S

5. Cashman JR
Biocatalysts in detoxication of drugs abuse.
NIDA Res. Monograph 173 (1997) 225-258

6. Charbonnier JB, Gigant B, Golinelli-Pimpaneau B & Knossow M
Similarities of hydrolytic antibodies revealed by their X-ray structures: a review.
Biochimie 79 (1997) 653-660

7. Charbonnier JB, Golinelli-Pimpaneau B, Gigant B, Tawfik DS, Chap R, Schlinder DG, Kim SH, Green BS, Eshhar Z & Knossow M
Structural convergence in the active sites of a family of catalytic antibodies.
Science 275 (1997) 1140-1142

8. Chen
Antibody catalysis of cyclohexadienone rearrangements.
Enzyme Microb. Technol. 20 (1997) 558

9. Fastrez J
In vivo versus in vitro screening or selection for catalytic activity in enzymes and abzymes.
Mol. Biotechnol. 7 (1997) 37-55

10. Fox T, Scanlan TS & Kollman PA
Ligand binding in the catalytic antibody 17E8. A free energy perturbation calculation study.
J. Am. Chem. Soc. 119 (1997) 11571-11577.

11. Gao C, Lin CH, Lo CHL, Mao S, Wirsching P, Lerner RA & Janda KD
Making chemistry selectable by linking to infectivity.
Proc. Natl. Acad. Sci. USA 94 (1997) 11777-11782

12. Generalov II, Konorev MR, Okulich VK, Yupatov GI & Generalova AG
Enzyme-like IgG activity in gastroduodenal pathology.
Immunol. Lett. 56 (1997) 309

13. Genre-Grandpierre A, Tellier C, Loirat MJ, Blanchard D, Hodgson DRW, Hollfelder F & Kirby AJ
Catalysis of the Kemp elimination by antibodies elicited against a cationinc hapten.
Bioorg. Med. Chem. Lett. 7 (1997) 2497-2502

14. Gigant B, Charbonnier JB, Eshhar Z, Green BS & Knossow M
X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc. Natl. Acad. Sci. USA 94 (1997) 7857-7861

15. Gigant B, Charbonnier JB, Golinelli-Pimpaneau, Zemel RR, Eshhar Z, Green BS & Knossow M
Mechanism of inactivation of a catalytic antibody by p-nitrophenyl esters.
Eur. J. Biochem. 246 (1997) 471-476

16. Gololobov GV, Rumbley CA, Rumbley JN, Schourov DV, Makarevich OI, Gabibov AG, Voss EW & Rodkey LS
DNA hydrolysis by monoclonal anti-ssDNA autoantibody BV 04-01: origins of catalytic activity.
Mol. Immunol. 34 (1997) 1083-1093

17. Gonzalez-Bello C, Abell C & Leeper FJ
Synthesis of tetrahydroquinolines, hexahydrobenzoindolizines and an aryl phosphonate linker for the generation of catalytic antibodies.
J. Chem. Soc., Perkin Trans. 7 (1997) 1017-1024

18. Hasserodt J & Janda KD
Syntheses of octahydroquinoline-N-oxides: haptens design to elicit catalytic antibodies that control a terpenoid-like cascad cyclisation.
Tetrahedron 53 (1997) 11237-11256

19. Hasserodt J, Janda KD & Lerner RA
Formation of bridge-methylated decalins by antibody-catalyzed tandem cationic cyclization.
J. Am. Chem. Soc. 119 (1997) 5993-5998

20. Hu YJ, Ji YY, Wu YL, Yang BH & Yeh M
Polyclonal catalytic antibody for hetero-cycloaddition of hepta-1,3-diene with ethyl glyoxylate. An approach to the synthesis of 2-nonulosonic acid analogs.
Bioorg. Med. Chem. Lett. 7 (1997) 1601-1606

21. Isomura S, Haruna M & Ito K
Design and synthesis of hapten to induce phospholipase A2-like catalytic antibody.
Bioorg. Med. Chem. Lett. 7 (1997) 251-254

22. Janda KD, Lo LC, Lo CHL, Sim MM, Wang R, Wong CH & Lerner RA
Chemical selection for catalysis in combinatorial antibody libraries.
Science 275 (1997) 945-948

23. Kanyshkova TG, Semenov DV, Khlimankov DY, Buneva VN & Nevinsky GA
DNA-hydrolyzing activity of the light chain of IgG antibodies from milk of healthy human mothers.
FEBS Letters 416 (1997) 23-26

24. Kim SH, Schindler DG, Lindner AB, Tawfik DS & Eshhar Z
Expression and characterization of recombinant single-chain Fv and Fv fragments derived from a set of catalytic antibodies.
Mol. Immunol. 34 (1997) 891-906

25. Kohda K, Kakehi M, Ohtsuji Y, Tagaki M & Imanaka T
Studies of high thermostability and peroxidase activity of recombinant antibody L chain-porphyrin Fe(III) complex.
FEBS Letters 407 (1997) 280-284

26. Landry DW
Immunotherapy for cocaine addiction.
Sci. Am. 276 (1997) 42-45

27. Landry DW & Yang GX
Anti-cocaine catalytic antibodies : a novel approach to the problem of addiction.
J. Addict Dis. 16 (1997) 01-017

28. Li Y & Sen D
Toward an efficient DNAzyme.
Biochemistry 36 (1997) 5589-5599

29. Lin CH, Hoffman TZ, Wirsching P, Barbas III CF, Janda KD & Lerner RA
On roads not taken in the evolution of protein catalysts: antibody steroid isomerases that use an enamine mechanism.
Proc. Natl. Acad. Sci. USA 94 (1997) 11773-11776

30. Liu D, Yu Y, Wong WKR, Zhao X & Zhang J
An enzyme-like polyclonal antibody capable of catalyzing ester hydrolysis.
Enzyme Microb. Technol. 20 (1997) 24-31

31. Lo CHL, Wentworth P, Jung KW, Yoon J, Ashley JA & Janda KD
Reactive immunization strategy generates antibodies with high catalytic preficiencies.
J. Am. Chem. Soc. 119 (1997) 10251-10252.

32. Miller GP, Posner BA & Benkovic SJ
Expanding the 43C9 class of catalytic antibodies using a chain-shuffling approach.
Bioorg. Med. Chem. 5 (1997) 581-590

33. Miyashita H, Hara T, Tanimura R, Fukuyama S, Cagnon C, Kohara A & Fujii I
Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization.
J. Mol. Biol. 267 (1997) 1247-1257

34. Mu Y & Gibbs RA
Design and synthesis of chiral and racemic phosphonate-based haptens for the induction of aldolase catalytic antibodies.
Bioorg. Med. Chem. 5 (1997) 1327-1337

35. Paul S, Li L, Kalaga R, O'Dell J, Dannenbring RE Jr, Swindells S, Hinrichs S, Caturegli P & Rose NR
Characterization of thyroglobulin-directed and polyreactive catalytic antibodies in autoimmune disease.
J. Immunol. 159 (1997) 1530-1536

36. Persidis A
Catalytic antibodies. Some companies are taking an active interest in this promising technology.
Nature Biotechnol. 15 (1997) 1313-1315

37. Resmini M, Vigna R, Simms C, Barber NJ, Hagi-Pavli EP, Watts AB, Verma C, Gallacher & Brocklehurst K
Characterization of the hydrolytic activity of a polyclonal antibody preparation by pH-dependence and chemical modification studies: evidence for the involvement of Tyr and Arg side chains as hydrogen-bond donors.
Biochem. J. 326 (1997) 279-287

38. Shchurov DV
Catalytic antibodies (russian)
Mol. Biol. (Mosk) 31 (1997) mai-15

39. Smithrud DB & Benkovic SJ
The state of antibody catalysis.
Curr. Opin. Biotechnol. 8 (1997) 459-466

40. Smithrud DB, Benkovic PA, Benkovic SJ, Taylor CM, Yager KM, Witherington J, Philips BW, Sprengeler PA, Smith III AB & Hirschmann R
Investigations of an antibody ligase.
J. Am. Chem. Soc. 119 (1997) 278-282

41. Sun M & Paul S
Altered cleavage site spreference of a proteolytic antibody light chain induced by denaturation.
FEBS Letters 407 (1997) 289-290

42. Sun M, Gao QS, Kirnarsky L, Rees A & Paul S
Cleavage specificity of a proteolytic antibody light chain and effects of the heavy chain variable domain.
J. Mol. Biol. 271 (1997) 374-385

43. Tawfik DS, Lindner AB, Chap R, Eshhar Z & Green BS
Efficient and selective p-nitrophenyl-ester-hydrolyzing antibodies elicited by a p-nitrobenzyl phosdphonate hapten.
Eur. J. Biochem. 244 (1997) 619-626

44. Ulrich HD, Mundorff E, Santarsiero BD, Driggers EM, Stevens RC & Schultz PG
The interplay between binding energy and catalysis in the evolution of a catalytic antibody.
Nature 389 (1997) 271-275

45. Wade H & Scanlan TS
The structural and functional basis of antibody catalysis.
Annu. Rev. Biophys. Biomol. Struct. 26 (1997) 461-493

46. Wedemayer GJ, Patten PA, Wang LH, Schultz PG & Stevens RC
Structural insights into the evolution of an antibody combining site.
Science 276 (1997) 1665-1669

47. Wedemayer GJ, Wang LH, Patten PA, Schultz PG & Stevens RC
Crystal structures of the free and liganded form of an esterolytic catalytic antibody.
J. Mol. Biol. 268 (1997) 390-400

48. Weiner DP, Wiemann T, Wolfe MM, Wentworth P & Janda KD
A pentacoordinate oxorheniium(V) metallochelate elicits antibody catalysts for phosphodiester cleavage.
J. Am. Chem. Soc. 119 (1997) 4088-4089

49. Wentworth P, Datta A, Smith S, Marshall A, Partridge LJ & Blackburm GM
Antibody catalysis of Bac2 aryl carbamate ester hydrolysis: a highly disfavored chemical process.
J. Am. Chem. Soc. 119 (1997) 2315-2316

50. Yli-Kauhaluoma J
Catalytic antibodies elicited by a hapten with twisted alpha-keto moiety.
Eur. J. Pharm. Sci. 5 (1997) S26

51. Yuan YR, Yang BH & Ji YY
An improved rapid method for selecting monoclonal antibodies with high catalytic activities.
J. Protein Chem. 16 (1997) 733-738

52. Zherdev AV, Dzantiev BB, Popov VO, Dzantiev LB, Kirby AJ, Sviridov VV & Iakovleva IV
Preparation and characteristics of antibodies to a sulfur-containing hapten, mimicking the transition state in lactamization reactions.
Prikl. Biok. Mikrob. 33 (1997) 624-631

53. Zhong G, Hoffmann T, Lerner RA, Danishefsky S & Barbas III CF
Antibody-catalyzed enantioselective Robinson annulation.
J. Am. Chem. Soc. 119 (1997) 8131-8132

54. Zhou ZS, Jiang N & Hilvert D
An antibody-catalyzed selenoxide elimination.
J. Am. Chem. Soc. 119 (1997) 3623-3624




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