1999


1. Almmonte RE, Shixian D, De Prada P, Stojanovic MN & Landry DW
Anti-cocaine catalytic antibodies.
Phosphorus Sulfur Silicon Relat. Elem. 144-6 (1999) 239-241

2. Bensel N, Bahr N, Reymond MT, Schenkels C & Reymond JL
Catalytic antibodies by fluorescence screening.
Helv. Chim. Acta 82 (1999) 44-52

3. Beste G, Schmidt FS, Stibora T & Skerra A
Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold.
Proc. Natl. Acad. Sci. USA 96 (1999) 1898-1903

4. Brummer O, Wentworth P, Weiner DP & Janda KD
Phosphorodithioates: synthesis and evaluation of new haptens for the generation of antibody acyl transferases.
Tetrahedron Lett. 40 (1999) 7307-7310

5. Coxon JM & Thorpe AJ
Theozymes for intramolecular ring cyclization reactions.
J. Am. Chem. Soc. 121 (1999) 10955-10957

6. Datta A, Wentworth P, Shaw JP, Simeonov A & Janda KD
Catalytically distinct antibodies prepared by the reactive immunization versus transition state analogue hapten manifolds.
J. Am. Chem. Soc. 121 (1999) 10461-10467

7. De Lauzon S, Desfosses B, Mansuy D & Mahy JP
Studies of the reactivity of artificial peroxidase-like hemoproteins based on antibodies elicited against a specifically designed ortho-carboxy substituted tetraarylporphyrin.
FEBS Letters 443 (1999) 229-234

8. Du M, Guo Z & Jin S
A new monoclonal anti-idiotypic catalytic antibody with a CPA-like activity.
Bioorg. Med. Chem. Lett. 9 (1999) 1487-1492

9. Esroy O, Fleck R, Blanco MJ & Masamune S
Design and syntheses of three haptens to generate catalytic antibodies that cleave amide bonds with nucleophilic catalysis.
Bioorg. Med. Chem. 7 (1999) 279-286

10. Friboulet A, Avalle B, Débat H & Thomas D
A possible role of catalytic antibodies in metabolism.
Immunol. Today 20 (1999) 474-475

11. Gao C, Brümmer O, Mao S & Janda KD
Selection of human metalloantibodies from a combinatorial phage single-chain antibody library.
J. Am. Chem. Soc. 121 (1999) 6517-6518

12. Geymayer P, Bahr N & Reymond JL
A general fluorogenic assay for catalysis using antibody sensor.
Chem. Eur. J. 5 (1999) 1006-1012

13. Gigant B, Golinelli B, Charbonnier JB, Eshhar Z, Green BS & Knossow M
Structures of esterase-like catalytic antibodies.
Phosphorus Sulfur Silicon Relat. Elem. 144-6 (1999) 121-124

14. Gigant B, Tsumuraya T, Fujii I & Knossow M
Diverse structural solutions to catalysis in a family of antibodies.
Structure 7 (1999) 1385-1393

15. Gololobov G, Sun M & Paul S
Innate antibody catalysis.
Mol. Immunol. 36 (1999) 1215-1222

16. Gruber K, Zhou B, Houk KN, Lerner RA, Shevlin CG & Wilson IA
Structural basis for antibody catalysis of a disfavored ring closure reaction.
Biochemistry 38 (1999) 7062-7074

17. Grynszpan F & Keinan E
Opsin shift in aldolase antibody.
Bioorg. Med. Chem. Lett. 9 (1999) 2419-2424

18. Hagi-Pavli EP, Simms CS, Ostler EL, Brocklehurst K & Gallacher G
Synthesis of a transition state analogue for the hydrolysis of cocaine: assistance to phosphonylation of a 3 beta-hydroxytropane by a neighbouring amide group.
Bioorg. Med. Chem. Lett. 9 (1999) 1881-1884

19. Hasselrodt J
Organic synthesis supported by antibody catalysis.
Synlett. 12 (1999) 2007-2022

20. Havsteen BH
An esterolytic antibody with vibrational properties of a catalytic H-chain and a non-catalytic L-chain.
J. Theor. Biol. 196 (1999) 377-387

21. Hifumi E, Okamoto Y & Uda T
Super catalytic antibody [I]: decomposition of targeted protein by its antibody light chain.
J. Biosci. Bioeng. 88 (1999) 323-327

22. Isomura S, Ito K & Haruna M
Phospholipase A(2)-like catalytic antibody.
Bioorg. Med. Chem. Lett. 9 (1999) 555-558

23. Iwabuchi Y, Kurihara S, Oda M & Fujii I
A modified bait and switch strategy for the generation of esterolytic abzymes using concerted catalytic mechanisms.
Tetrahedron Lett. 40 (1999) 5341-5344

24. Janda KD & Wentworth AD
A merging of chemistry and biology in terms of antibody catalysis.
Phosphorus Sulfur Silicon Relat. Elem. 146 (1999) 117-120

25. Kakimunuma H, Shimazaki K, Takahashi N, Takahashi K, Niihata S, Aoki Y, Hamada K, Matsushita H & Nishi Y
Comparison of phosphonate transition state analogs for inducing catalytic antibodies and evaluation of key structural factors by an ab initio study.
Tetrahedron 55 (1999) 2559-2572

26. Kawamura-Konishi Y, Fujie Y & Suzuki H
Kinetics of formation of antibody-ferric porphyrin complex with peroxidase activity.
J. Protein Chem. 18 (1999) 741-745.

27. Klein G & Reymond JL
Enantioselective fluorogenic assay of acetate hydrolysis for detecting lipase catalytic antibodies.
Helv. Chim. Acta 82 (1999) 400-407

28. Kristensen O, Vassylyev DG, Tanaka F, Morikawa K & Fujii I
A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: crystal structures of an abzyme at 1.8A resolution.
J. Mol. Biol. 281 (1999) 501-511

29. Kroon GJ, Martinez-Yamount MA, Krebs JF, Chung J, Dyson HJ & Wright PE
Backbone resonance assignments for the Fv fragment of the catalytic antibody NPN43C9 with bound p-nitrophenol.
J. Biomol. NMR 15 (1999) 83-84

30. Lacroix-Desmazes S, Moreau A, Sooryanarayana, Bonnemain C, Stieltjes N, Pashov A, Sultan Y, Hoebeke J, Kazatchkine MD & Kaveri SV
Catalytic activity of antibodies against factor VIII in patients with hemophila A.
Nature Medicine 5 (1999) 1044-1047

31. Lindner AB, Eshhar Z & Tawfik D
Conformational changes affect binding and catalysis by ester-hydrolising antibodies.
J. Mol. Biol. 285 (1999) 421-430

32. List B, Lerner RA & Barbas III CF
Enantioselective aldol cyclodehydrations catalyzed by antibody 38C2.
Organic Letters 1 (1999) 59-61

33. List B, Shabat D, Zhong G, Turner JM, Li A, Bui T, Anderson J, Lerner RA & Barbas III CF
A catalytic enantioselective route to hydroxy-substituted quaternary carbon centers: resolution of tertiary aldols with a catalytic antibody.
J. Am. Chem. Soc. 121 (1999) 7283-7291

34. Liu JQ, Shi CB, Luo GM, Liu Z, Zhang GL, Ma WY & Shen JC
An Fv catalytic antibody with high glutathione peroxidase activity.
Materials Sci. Eng. 10 (1999) 131-134

35. Ma LM, Sweet EH & Schultz PG
Selective antibody-catalyzed solvolysis of endo-2-norbonyl mesylate.
J. Am. Chem. Soc. 121 (1999) 10227-10228

36. Martin AB & Schultz PG
Opportunities at the interface of chemistry and biology.
Trends Cell. Biol. 9 (1999) M24-M28

37. Matsuura K, Ikoma S, Watanabe M, Togawa A & Sinohara H
Some Bence-Jones proteins enter cultured renal tubular cells, reach nuclei and induce cell death.
Immunology 98 (1999) 584-589

38. Nimri S & Keinan E
Antibody-metalloporphyrin catalytic assembly mimics natural oxidation enzymes.
J. Am. Chem. SoC. 121 (1999) 8978-8982

39. Ohage EC, Wirtz P, Barnikov J & Steipe B
Intrabody construction and expression. II. A synthetic catalytic Fv fragment.
J. Mol. Biol. 291 (1999) 1129-1134

40. Ono M & Wada Y
Study on substrate specificity of hydrolytic catalytic antibody.
J. Synth. Org. Chem. Jap. 57 (1999) 867-875

41. Paschall CM, Hasserodt J, Jones T, Lerner RA, Janda KD & Christianson DW
Convergence of catalytic antibody and terpene cyclase mechanisms: polyene cyclization directed by carbocation-&pi interactions.
Angew. Chem. 38 (1999) 1743-1747

42. Qi DH, uo GM, Zhou L & Yang TS
Protection of myocardial mitochondria against oxidative damage by selenium-containing abzyme m4G3.
Appl. Biochem. Biotechnol. 82 (1999) 167-173

43. Renard PY, Vayron P, Taran F & Mioskowski C
Design and synthesis of haptens for antibody catalyzed hydrolysis of organophosphorus nerve agents.
Tetrahedron Lett. 40 (1999) 281-284

44. Reymond JL
Catalytic antibodies for organic synthesis.
Top Curr. Chem. 200 (1999) 59-93

45. Ritzeler O, Klein G & Reymond JL
Atropisomeric transition state analogs.
Phosphorus Sulfur Silicon Relat. Elem. 146 (1999) 243-246

46. Romesberg FE & Schultz PG
A mutational study of a Diels-Alderase catalytic antibody.
Bioorg. Med. Chem. Lett. 9 (1999) 1741-1744

47. Shabat D, List B, Lerner RA & Barbas CF 3rd
A short enantioselective synthesis of 1-deoxy-L-xylulose by antibody catalysis.
Tetrahedron Lett. 40 (1999) 1437-1440

48. Shabat D, Rader C, List B, Lerner RA & Barbas III CF
Multiple event activation of a generic prodrug trigger by antibody catalysis.
Proc. Natl. Acad. Sci. USA 96 (1999) 6925-6930

49. Shulman H & Keinan E
Substrate-selective mechanisms in biocatalysis demonstrated with versatile and efficient aldolase antibody.
Bioorg. Med. Chem. Lett. 9 (1999) 1745-1750

50. Sinha SC, Sun J, Miller G, Barbas III CF & Lerner RA
Sets of aldolase antibodies with antipodal reactivities. Formal synthesis of epothilone E by large-scale antibody-catalyzed resolution of thiazole aldol.
Organic Letters 1 (1999) 1623-1626

51. Spivak DA, Hoffman TZ, Moore AH, Taylor MJ & Janda KD
A comparison of flexible and constrained haptens in eliciting antibody catalysts for paraoxon hydrolysis.
Bioorg. Med. Chem. 7 (1999) 1145-1150

52. Stevenson JD, Dietel A & Thomas NR
A chemiluminescent catalytic antibody.
Chem. Commun. 20 (1999) 2105-2106

53. Takahashi N, Kakinuma H, Hamada K, Shimazaki K, Takahashi K, Niihata S, Aoki Y, Matsushita H & Nishi Y
Efficient screening for catalytic antibodies using a short transition-state analog and detailed characterization of selected antibodies.
Eur. J. Biochem. 261 (1999) 108-112

54. Tanaka F, Almer H, Lerner RA & Barbas III CF
Catalytic single-chain antibodies possessing ß-lactamase activity selected from a phage displayed combinatorial library using a mechanism-based inhibitor.
Tetrahedron Lett. 40 (1999) 8063-8066

55. Tanaka F, Lerner RA & Barbas III CF
Thiazolium-dependent catalytic antibodies produced using covalent modification strategy.
Chem. Commun. 20 (1999) 1383-1384.

56. Tantillo DJ & Houk KN
Fidelity in hapten design: how analogous are phosphonate haptens to the transition states for alkaline hydrolyses of aryl esters?
J. Org. Chem. 64 (1999) 3066-3076

57. Taran F, Renard PY, Creminon C, Valleix A, Frobert Y, Pradelles P, Grassi J & Mioskowski C
Competitive immunoassay (Cat-EIA), a helpful technique for catalytic antibody detection. Part I.
Tetrahedron Lett. 40 (1999) 1887-1890

58. Taran F, Renard PY, Creminon C, Valleix A, Frobert Y, Pradelles P, Grassi J & Mioskowski C
Competitive immunoassay (Cat-EIA), a helpful technique for catalytic antibody detection. Part II.
Tetrahedron Lett. 40 (1999) 1891-1894.

59. Tarasow tM & Eaton BE
The Diels-Alder reaction and biopolymer catalysis.
Cell. Mol. Life Sci. 55 (1999) 1463-1472

60. Taylor MJ, Yli-Kauhaluoma JT, Ashley JA, Wirsching P, Lerner RA & Janda KD
The alpha-ketoamide group: a new motif for the elicitation of catalytic antibodies for acyl-transfer reactions.
J. Chem. Soc. Perkin Trans. 9 (1999) 1133-1134

61. Thayer MM, Olender EH, Arvai AS, Koike CK, Canestrelli IL, Stewart JD, Benkovic SJ, Getzoff ED & Roberts VA
Structural basis for amide hydrolysis catalyzed by the 43C9 antibody.
J. Mol. Biol. 291 (1999) 329-345

62. Van den Berg RJBHN, Noort D, Milder-Enacache ES, Van der Marel GA, Van Boom JH & Benschop HP
Approach toward a generic treatment of Gram-negative infections: synthesis of haptens for catalytic antibody mediated cleavage of the interglycosidic bond in lipid A.
Eur. J. Org. Chem. 10 (1999) 2593-2600

63. Vlasov AV, Helm M, Naumov VA, Breusov AA, Buneva VN, Florentz C, Giege R & Nevinsky GA
Hydrolysis of tRNA with serum autoantibodies of patients with autoimmune diseases.
Mol. Biol. 33 (1999) 766-771

64. Wada Y & Ono M
Binding specificity of hydrolytic catalytic antibody. Lessons from the diverse immune system.
J. Protein Chem. 18 (1999) 199-204

65. Wade H & Scanlan TS
Expression of binding energy on an antibody reaction coordinate.
J. Am. Chem. Soc. 121 (1999) 11935-11941

66. Wade H & Scanlan TS
Remote binding energy in antibody catalysis: studies of a catalytically unoptimized specificity pocket.
J. Am. Chem. Soc. 121 (1999) 1434-1443

67. Wentworth P & Janda KD
Antibody catalysis of phosphodiester hydrolysis: a survey of hapten strategies.
Phosphorus Sulfur Silicon Relat. Elem. 146 (1999) 247-250

68. Xu J, Deng Q, Chen J, Houk KN, Bartek J, Hilvert D & Wilson IA
Evolution of shape complementarity and catalytic efficiency from a primordiazl antibody template.
Science 286 (1999) 2345-2348

69. Yamagushi H, Oka F, Kamachi M & Harada A
Direct observation of supramolecular structures of porphyrin dimer antibody complexes by atomic force microscopy.
Kobunshi-Ronbunshu 56 (1999) 660-666

70. Yang PL & Schultz PG
Mutational analysis of the affinity maturation of antibody 48G7.
J. Mol. Biol. 294 (1999) 1191-1201

71. Yli-Kauhaluoma J; Humppi T & Yliniemela A
Hydrolysis of organophosphorus nerve agent soman by the monoclonal antibodies elicited against an oxyphosphorane hapten.
Acta Chem. Scand. 53 (1999) 473-479

72. Zhong GF, Lerner RA & Barbas CF
Broadening the aldolase catalytic antibody repertoire by combining reactive immunization and transition state theory: new enantio and diastereoselectivities.
Angew. Chem. 38 (1999) 3738-3741




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