


Multiphysics study of the dynamics, resistance and delivery potential of deformable Micro-Capsules
Grant Agreement number: 772191 — MultiphysMicroCaps — ERC-2017-COG

Objectives
The objective is to study the behavior of liquid-core deformable microcapsule using
sophisticated numerical models and microexperimental techniques developed
synergistically. The project will pave the way to the generation of new
generations of microvectors for active substances, thus offering alternatives
to the use of nanoparticles. It proposes novel paradigms to model the flow and
deformation of microcapsules both experimentally and numerically, in order to
find the tradeoff between the quantity of encapsulated substance and the
mechanical resistance of the capsule. The challenge will be to tune the
mechanical properties to prevent (or favor) rupture during flow and guarantee
that the particles reaches the desired location.
The project will allow gathering a large number of collaborators and combing fundamental
studies aiming at pushing forward the limit of knowledge on fluid-structure
interactions at low inertia, with applied studies such as the encapsulation of
natural anti-cancer substances.